Esx 1 Tuberculosis

Mycobacteriumrculosis

Mycobacteriumrculosis


.rculosis Edinb . 2009 Dec;:S74-6. doi: 10.1016/S1472-9792 09 70017-4. Mycobacterium .rculosis ESX-1 system-secreted protein ESAT-6 . - M. .rculosis ESX-1 is required for virulence in mice, growth in macrophages, and the suppression of macrophage inflammatory and immune .We show that in contrast to ESX-1, the effector proteins secreted by ESX-5 are not required for the translocation of Mycobacterium .rculosis or Mycobacterium .CFP-10 also known as ESAT-6-like protein esxB or secreted antigenic protein MTSA- kDa culture filtrate antigen CFP-10 is a protein that is encoded by the esxB gene. CFP-10 is a 10 kDa secreted antigen from Mycobacterium .rculosis. It forms a 1:1 heterodimeric complex with ESAT-6. In Mycobacterium .rculosis, the core components of the whole ESX-1 .



CFP-10 also known as ESAT-6-like protein esxB or secreted antigenic protein MTSA- kDa culture filtrate antigen CFP-10 is a protein that is encoded by the esxB gene. CFP-10 is a 10 kDa secret ..rculosis Edinb . 2009 Dec;:S74-6. doi: 10.1016/S1472-9792 09 70017-4. Mycobacterium .rculosis ESX-1 system-secreted protein ESAT-6 .We show that in contrast to ESX-1, the effector proteins secreted by ESX-5 are not required for the translocation of Mycobacterium .rculosis or Mycobacterium .The ESX-1 type VII secretion system is required for the virulence of several Gram-positive and mycobacterial pathogens, including Mycobacterium .rculosis, .


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