- Other people can have weak immune systems, too, especially people with any of these conditions: HIV infection the virus that causes AIDS Substance abuse. Silicosis. Diabetes mellitus. Severe kidney disease. Low body weight. Organ transplants. Head and neck cancer.. - A number of diseases and medications can weaken your immune system, including: HIV/AIDS. Diabetes. Severe kidney disease. Certain cancers. Cancer treatment, such as chemotherapy. Drugs to prevent rejection of transplanted organs. Some drugs used to treat rheumatoid arthritis, Crohn 's disease and psoriasis. Malnutrition..
There are a number risk factors for .rculosis infection; worldwide the most important of these is HIV. Co-infection with HIV is a particular problem in . For persons whose immune systems are weak, especially those with HIV infection, the risk of developing TB disease is much higher than for .Several medical conditions are risk factors for TB and for poor TB treatment results, while TB can complicate the disease course of some diseases. It is therefore ..rculosis TB is an infectious disease that 's transmitted when someone inhales infected sputum from the air. People who have a higher risk of contracting TB .
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